Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia.

@article{Karp1993PontineAE,
  title={Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia.},
  author={Barbara Illowsky Karp and Robert Laureno},
  journal={Medicine},
  year={1993},
  volume={72 6},
  pages={359-73}
}
Neurologic disorders developing after correction of severe, symptomatic hyponatremia were studied in 14 patients. None had a hypoxic event or other identifiable cause for the neurologic illness. Neurologic deterioration began about 3 days after correction and often followed a period of improvement in hyponatremic encephalopathy. Although the symptoms were as mild as transient confusion in 1 patient, they were more severe in the others. Typically, spastic quadriparesis, pseudobulbar palsy, and… CONTINUE READING

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