Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia

@inproceedings{Sarkaki2015PomegranateSH,
  title={Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia},
  author={Alireza Sarkaki and Yaghoub Farbood and Shieda Hashemi and Maryam Rafiei Rad},
  booktitle={Avicenna journal of phytomedicine},
  year={2015}
}
OBJECTIVES Estrogen deficit following menopause results in cognitive behaviors impairment. This study aimed to evaluate the effects of pomegranate seed extract (PGSE) on avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO) in ovariectomized (OVX) rats. MATERIALS AND METHODS Adult female Wistar rats were divided randomly into eight groups with 8 rats in each group: 1) Sham-operated for ovaries and 2CCAO (ShO); 2) OVX and sham operated for ischemia (OShI); 3-7… CONTINUE READING