Polyunsaturated fatty acids regulate cell proliferation, extracellular matrix mineralization and gene expression in a gilthead seabream skeletal cell line

@inproceedings{Viegas2012PolyunsaturatedFA,
  title={Polyunsaturated fatty acids regulate cell proliferation, extracellular matrix mineralization and gene expression in a gilthead seabream skeletal cell line},
  author={Michael N. Viegas and Jorge Dias and M Leonor Cancela and Vincent Laiz{\'e}},
  year={2012}
}
  • Michael N. Viegas, Jorge Dias, +1 author Vincent Laizé
  • Published 2012
  • Biology
  • Summary Polyunsaturated fatty acids (PUFAs) such as arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are defining components of farmed fish feeds. They are known effectors of bone metabolism and may reduce the occurrence of skeleton deformities in farmed fish, given that dietary levels are optimized. Underlying mechanisms of bone-related effects of PUFAs are however poorly understood. An in vitro cell system developed from gilthead seabream vertebra and… CONTINUE READING

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