Polyunsaturated fatty acids and endocannabinoids in health and disease

@article{Freitas2018PolyunsaturatedFA,
  title={Polyunsaturated fatty acids and endocannabinoids in health and disease},
  author={H{\'e}rcules Rezende Freitas and Alinny Rosendo Isaac and Renato Malcher-Lopes and Bruno L. Diaz and Isis H. Trevenzoli and Ricardo Augusto de Melo Reis},
  journal={Nutritional Neuroscience},
  year={2018},
  volume={21},
  pages={695 - 714}
}
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic acid, DHA, and eicosapentaenoic acid, EPA) or of omega-6 (arachidonic acid, ARA) synthesized from membrane phospholipids and used as a precursor for endocannabinoids (ECs). They mediate significant effects in the fine-tune adjustment of body homeostasis. Phyto- and synthetic cannabinoids also rule the daily life of billions worldwide, as they are involved in obesity, depression and drug addiction. Consequently… 
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