Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis

  title={Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis},
  author={Jingnan Chen and Y. -J. Wei and Xinyu Chen and Jingjing Jiao and Yu Zhang},
Polyunsaturated fatty acids (PUFA), a group of nourishing and health-promoting nutrients, ameliorate age-related chronic diseases. However, how PUFA especially n-3 PUFA exert anti-aging functions remains poorly understood. Here we link fish oil, docosahexaenoic acid (DHA) and arachidonic acid (AA) to the aging etiology via a redox-telomere-antioncogene axis based on D-galactose-induced aging mice. Both fish oil and PUFA enhanced hepatic superoxide dismutase (SOD) and catalase activities and… CONTINUE READING
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