Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL

@article{Chyb1999PolyunsaturatedFA,
  title={Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL},
  author={Sylwester Chyb and Padinjat Raghu and Roger C. Hardie},
  journal={Nature},
  year={1999},
  volume={397},
  pages={255-259}
}
Phototransduction in invertebrate microvillar photoreceptors is thought to be mediated by the activation of phospholipase C (PLC), but how this leads to gating of the light-sensitive channels is unknown,. Most attention has focused on inositol-1,4,5-trisphosphate, a second messenger produced by PLC from phosphatidylinositol-4,5-bisphosphate; however, PLC… CONTINUE READING