Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica.

@article{Jarius2008PolyspecificAI,
  title={Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica.},
  author={Sven Jarius and Diego Franciotta and Roberto Bergamaschi and Sebastian Rauer and K. P. Wandinger and H Felicitas Petereit and Martin Maurer and Hayrettin Tumani and Angela Vincent and Peter Eichhorn and Brigitte T. Wildemann and Manfred T. Wick and Raymond Voltz},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2008},
  volume={79 10},
  pages={1134-6}
}
BACKGROUND A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80-100% of patients with multiple sclerosis (MS), but has not to date been evaluated in patients with neuromyelitis optica (NMO). AIMS To evaluate whether MRZR distinguishes NMO and MS. METHODS 20 patients with NMO and 42 with MS were included. The intrathecal synthesis of antibodies against measles, rubella and… CONTINUE READING

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Neuromyelitis optica.

Current treatment options in neurology • 2008

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