Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions.

@article{Coors2005Polysorbate8I,
  title={Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions.},
  author={Esther A Coors and Heidi Seybold and Hans Friedrich Merk and Vera Mahler},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  year={2005},
  volume={95 6},
  pages={
          593-9
        }
}
BACKGROUND Polyoxyethylene-sorbitan-20-monooleate (also known as polysorbate 80 and Tween 80) is a solubilizing agent ubiquitously used in nutritives, creams, ointments, lotions, and multiple medical preparations (e.g., vitamin oils, vaccines, and anticancer agents) and as an additive in tablets. Whereas its relevance as a contact allergen has declined during the past decades, it is of current relevance as a "hidden" inductor of anaphylactoid reactions. OBJECTIVE To identify polysorbate 80… CONTINUE READING
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