Polysilsesquioxanes and Oligosilsesquioxanes Substituted by Alkylammonium Salts as Antibacterial Biocides

@article{Chojnowski2006PolysilsesquioxanesAO,
  title={Polysilsesquioxanes and Oligosilsesquioxanes Substituted by Alkylammonium Salts as Antibacterial Biocides},
  author={Julian Chojnowski and Witold Fortuniak and Pawel Rosciszewski and Władysław Werel and Jagoda Łukasiak and Wojciech Kamysz and Rafał Hałasa},
  journal={Journal of Inorganic and Organometallic Polymers and Materials},
  year={2006},
  volume={16},
  pages={219-230}
}
Octa(3-chloropropylsilsesquioxane), (T-ClPr)8, and a soluble, low molecular weight, poly(3-chloropropylsilsesquioxane) were subjected to a reaction with dimethyl-n-octylamine to convert part or almost all the chloropropyl groups to corresponding quaternary ammonium salt (QAS) groups. Polysilsesquioxanes containing secondary n-amylammonium salt (SAS) groups were synthesized by reaction of n-alkyl bromides with poly(3-aminopropylsilsesquioxane) of limited molecular weight or by amination of n… 
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TLDR
The antibacterial properties of the ammonium-terminated hyperbranched polycarbosilanes and dendrimers have been evaluated showing that they act as potent biocides against Gram-positive and Gram-negative bacterial strains.
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