• Biology, Medicine
  • Published in Phytotherapy research : PTR 2017
  • DOI:10.1002/ptr.5745

Polysaccharide of Danggui Buxue Tang, an Ancient Chinese Herbal Decoction, Induces Expression of Pro‐inflammatory Cytokines Possibly Via Activation of NF&kgr;B Signaling in Cultured RAW 264.7 Cells

@article{Gong2017PolysaccharideOD,
  title={Polysaccharide of Danggui Buxue Tang, an Ancient Chinese Herbal Decoction, Induces Expression of Pro‐inflammatory Cytokines Possibly Via Activation of NF&kgr;B Signaling in Cultured RAW 264.7 Cells},
  author={Amy G. W. Gong and Laura M L Zhang and Candy T. W. Lam and Miranda Li Xu and Huai You Wang and Huang-Quan Lin and Tina T X Dong and Karl Wah-Keung Tsim},
  journal={Phytotherapy Research},
  year={2017},
  volume={31},
  pages={274–283}
}
Danggui Buxue Tang (DBT) is an ancient Chinese herbal decoction containing two herbs, Astragali Radix (AR) and Angelicae Sinensis Radix (ASR): this herbal decoction serves as dietary supplement for women during menopause. DBT has been known to modulate immune responses, and its polysaccharide is proposed to be one of the active components. However, the polysaccharide-induced signaling in immune activation is not revealed. Here, we are identifying that the immune activation, triggered by DBT… CONTINUE READING

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