Polysaccharide from Angelica sinensis protects chondrocytes from H2O2-induced apoptosis through its antioxidant effects in vitro.

@article{Zhuang2016PolysaccharideFA,
  title={Polysaccharide from Angelica sinensis protects chondrocytes from H2O2-induced apoptosis through its antioxidant effects in vitro.},
  author={Chao Zhuang and Nan-wei Xu and Gong-Ming Gao and Su Ni and Kai-Song Miao and C X Li and Liming Wang and Hong-Guang Xie},
  journal={International journal of biological macromolecules},
  year={2016},
  volume={87},
  pages={322-8}
}
This study aimed to explore the protective effects of Angelica sinensis polysaccharide (ASP) on rat chondrocyte injury induced by hydrogen peroxide (H2O2). Rat chondrocytes were cultured and treated with different concentrations of ASP alone or in combination with H2O2, and they were measured with cell viability, apoptosis, release of inflammatory cytokines, such as interleukin-1beta (IL-1β) and tumor necrosis factor-alpha (TNF-α), activity of superoxide dismutase (SOD), and catalase (CAT), and… CONTINUE READING

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