Polysaccharide encapsulated bacterial infection in sickle cell anemia: A thirty year epidemiologic experience

@article{Wong1992PolysaccharideEB,
  title={Polysaccharide encapsulated bacterial infection in sickle cell anemia: A thirty year epidemiologic experience},
  author={W. Wong and D. Powars and L. Chan and A. Hiti and C. Johnson and G. Overturf},
  journal={American Journal of Hematology},
  year={1992},
  volume={39}
}
Annual age‐specific incidence rates of Streptococcus pneumoniae or Haemophilus influenzae bacterial septicemia in sickle cell anemia (SS) were determined for the years of 1957 through 1989. Forty‐nine patients had 64 episodes of septicemia among a population of 786 SS patients observed for 8,138 person‐years. Peak frequency of infection occurred between 1968‐1971 and 1975‐1981 with a conspicuous absence of episodes in 1972, 1973, 1982‐1984, and 1986‐1987, thus demonstrating cycles of high and… Expand
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