Polypyrrole-heparin composites as stimulus-responsive substrates for endothelial cell growth.

  title={Polypyrrole-heparin composites as stimulus-responsive substrates for endothelial cell growth.},
  author={Brett Garner and A Georgevich and A. J. Hodgson and Litian Liu and Gordon G. Wallace},
  journal={Journal of biomedical materials research},
  volume={44 2},
Heparin is a potent anticoagulant which can be immobilized on biomaterial surfaces to increase their hemocompatability. In the present work, we have electrochemically synthesized composites comprising heparin and the electrically conducting polymer polypyrrole. The incorporation and exposure of heparin were controlled by varying key conditions of polymer synthesis (i.e., applied current and synthesis time). The resulting composite polymers were electroactive after synthesis and the amount of… CONTINUE READING

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