Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone.

@article{Okada1996PolyprenylDS,
  title={Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone.},
  author={Kiyoshi Okada and Katsuhisa Suzuki and Yuji Kamiya and Xiao Fan Zhu and Shingo Fujisaki and Yuhei Nishimura and Tokuzo Nishino and Tsuyoshi Nakagawa and Makoto Kawamukai and Hideyuki Matsuda},
  journal={Biochimica et biophysica acta},
  year={1996},
  volume={1302 3},
  pages={217-23}
}
Ubiquinone, known as a component of the electron transfer system in many organisms, has a different length of the isoprenoid side chain depending on the species, e.g., Escherichia coli, Saccharomyces cerevisiae and humans have 8, 6, and 10 isoprene units in the side chain, respectively. No direct evidence has yet shown what factors define the length of the side chain of ubiquinone. Here we proved that the polyprenyl diphosphate that was available in cells determined the length of the side chain… CONTINUE READING

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