Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.

@article{RamrezBosc2012PolypodiumLE,
  title={Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.},
  author={A. Ram{\'i}rez-Bosc{\'a} and P. Zapater and I. Betlloch and F. Albero and A. Mart{\'i}nez and J. Dı́az-Alperi and J. Horga},
  journal={Actas dermo-sifiliograficas},
  year={2012},
  volume={103 7},
  pages={
          599-607
        }
}
INTRODUCTION Topical corticosteroids are used to treat inflammation and relieve itching in atopic dermatitis, but their use is limited by adverse reactions. [...] Key MethodPATIENTS AND METHODS We performed a phase IV randomized, double-blind, placebo-controlled, multicenter trial involving 105 patients aged between 2 and 17 years who were receiving topical corticosteroids to treat moderate atopic dermatitis.Expand
Atopic Dermatitis: An Evidence-Based Treatment Update
  • J. Silverberg
  • Medicine
  • American Journal of Clinical Dermatology
  • 2014
TLDR
Investigator-initiated RCTs support the use of the systemic agents cyclosporine, methotrexate, azathioprine and mycophenolate mofetil, and in one RCT, petrolatum was found to be as effective as creams containing ceramides or glycyrrhetinic acid. Expand
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Polypodium leucotomos extract 240mg taken twice daily for 60 days was a safe and effective means for reducing the damaging effects of ultraviolet radiation. Expand
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The use of Polypodium leucotomos, a species of fern, has been reported to be beneficial in the treatment of atopic dermatitis, vitiligo, and psoriasis, and for prevention of polymorphic lightExpand
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The results suggest that a fixed Polypodium leucotomos/pomegranate combination provides a greater improvement of skin biophysical parameters compared to Polyp sodium leucotomyos alone in adult Caucasians. Expand
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Evaluation of the safety and efficacy of Chinese medicine treatment in the management of atopic dermatitis
Atopic dermatitis (AD) is a chronic, inflammatory skin rash which affects approximately 15-30% of children and 2-10% of adults and can significantly impair quality of life. The extended use of theirExpand
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