Polyphosphate kinase 1 is a pathogenesis determinant in Campylobacter jejuni.

  title={Polyphosphate kinase 1 is a pathogenesis determinant in Campylobacter jejuni.},
  author={Heather L Candon and Brenda J Allan and Cresson D Fraley and Erin C. Gaynor},
  journal={Journal of bacteriology},
  volume={189 22},
Campylobacter jejuni is the leading cause of bacterial gastroenteritis in the developed world. Despite its prevalence, relatively little is known about C. jejuni's precise pathogenesis mechanisms, particularly in comparison to other well-studied enteric organisms such as Escherichia coli and Salmonella spp. Altered expression of phosphate genes in a C. jejuni stringent response mutant, together with known correlations between the stringent response, polyphosphate (poly-P), and virulence in… CONTINUE READING


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