Polyphosphatase activity of CthTTM, a bacterial triphosphate tunnel metalloenzyme.

Abstract

Triphosphate tunnel metalloenzymes (TTMs) are a superfamily of phosphotransferases with a distinctive active site located within an eight-stranded beta barrel. The best understood family members are the eukaryal RNA triphosphatases, which catalyze the initial step in mRNA capping. The RNA triphosphatases characteristically hydrolyze nucleoside 5… (More)
DOI: 10.1074/jbc.M805392200

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