Polyphenols with antiulcerogenic action from aqueous decoction of mango leaves (Mangifera indica L.).

@article{Severi2009PolyphenolsWA,
  title={Polyphenols with antiulcerogenic action from aqueous decoction of mango leaves (Mangifera indica L.).},
  author={Juliana Aparecida Severi and Zeila Pinheiro Lima and H{\'e}lio Kushima and Alba Regina Monteiro Souza Brito and Lourdes Campaner dos Santos and Wagner Vilegas and Cl{\'e}lia Akiko Hiruma-Lima},
  journal={Molecules},
  year={2009},
  volume={14 3},
  pages={1098-110}
}
This study was designed to determine the gastroprotective effect of a Mangifera indica leaf decoction (AD), on different experimental models in rodents. The administration of AD up to a dose of 5 g/kg (p.o.) did not produce any signs or symptoms of toxicity in the treated animals, while significantly decreasing the severity of gastric damage induced by several gastroprotective models. Oral pre-treatment with AD (250, 500 or 1000 mg/kg) in mice and rats with gastric lesions induced by HCl… CONTINUE READING