Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants.

  title={Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants.},
  author={Nesma M. Salah and Nicholas J. Miller and George Paganga and L Tijburg and G. Paul Bolwell and C. Rice-evans},
  journal={Archives of biochemistry and biophysics},
  volume={322 2},
The purpose of this investigation was to establish the relative antioxidant activities in vitro of the flavanolic polyphenols, the catechins, and catechin-gallate esters. The relative antioxidant potentials were measured against radicals generated in the aqueous phase and against propagating lipid peroxyl radicals. The results show that in the aqueous phase their order of effectiveness as radical scavengers is epicatechin gallate (ECG) > epigallocatechin gallate (EGCG) > epigallocatechin (EGC… Expand
Mechanistic studies of catechins as antioxidants against radical oxidation.
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Evaluation of antioxidant activity of epigallocatechin gallate in biphasic model systems in vitro
  • Chun Hu, D. Kitts
  • Chemistry, Medicine
  • Molecular and Cellular Biochemistry
  • 2004
It is concluded that the particularly effective antioxidant properties of EGCG noted in both chemical and biological biphasic systems were related to a unique hydrophilic and lipophilic balance which enabled effective free radical scavenging. Expand