Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes.

@article{Gnjidic2012PolypharmacyCA,
  title={Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes.},
  author={Danijela Gnjidic and Sarah N Hilmer and Fiona M. Blyth and Vasi Naganathan and Louise M. Waite and Markus J. Seibel and Andrew J. McLachlan and Robert G Cumming and David J Handelsman and David G Le Couteur},
  journal={Journal of clinical epidemiology},
  year={2012},
  volume={65 9},
  pages={989-95}
}
OBJECTIVE This study aimed to determine an optimal discriminating number of concomitant medications associated with geriatric syndromes, functional outcomes, and mortality in community-dwelling older men. STUDY DESIGN AND SETTING Older men aged ≥ 70 years (n=1,705), enrolled in the Concord Health and Aging in Men Project were studied. Receiver operating characteristic curve analysis using the Youden Index and the area under the curve was performed to determine discriminating number of… CONTINUE READING