Polypeptides of cells transformed by RNA or DNA tumor viruses.

  title={Polypeptides of cells transformed by RNA or DNA tumor viruses.},
  author={Micheline Strand and J. Thomas August},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={74 7},
Proteins solubilized from normal BALB/3T3 cells and BALB/3T3 transformed by simian virus 40 or Kirsten sarcoma virus have been analyzed by two-dimensional gel electrophoresis and tryptic peptide mapping. A large fraction of the polypeptides of the virus-transformed cells, about 30%, were different from normal cells. In contrast to the marked differences between normal and transformed cells, the polypeptides of the DNA and RNA virus-transformed cells were almost identical. These findings were… CONTINUE READING