Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography.

@article{Bergeron1980PolypeptideHR,
  title={Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography.},
  author={John J. M. Bergeron and Richard A Rachubinski and Nick Searle and D Borts and R A Sikstrom and Barry I. Posner},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1980},
  volume={28 8},
  pages={824-35}
}
A tissue-screening survey employing quantitative radioautography was carried out at 2 min after the intravascular injection of 125I-insulin into laboratory rats. The results revealed a substantial binding of insulin to cells forming the proximal convoluted tubule in kidney, hepatocytes of liver, acinar cells of the pancreas, parenchymal cells of the adrenal… CONTINUE READING