Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome

  title={Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome},
  author={Carlos Eduardo Lassance Cabral and Pedro Gabriel Dantas Guedes and Therezinha Fonseca and Jos{\'e} Francisco Neto Rezende and Luiz Celso Cruz Jr. and Julius Smith},
  journal={Skeletal Radiology},
Abstract Mazabraud’s syndrome, though uncommon, is reported increasingly frequently. It represents an entity readily recognisable radiologically on MR imaging. Awareness of the syndrome, particularly when the myxoma is solitary, can prevent misdiagnosis of intramuscular myxomas (especially when large) as malignant mesenchymal tumors containing myxoid tissue. We review the 34 cases previously reported in the literature and include a recent case from our center. 
Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud’s syndrome
An extremely rare combination of a solitary IM and monostotic FD as a variant of Mazabraud’s syndrome is presented, and the importance of recognizing this rare coexistence for appropriate management of the patient is discussed.
Mazabraud's syndrome with sarcomatous transformation: scintigraphic and radiologic imaging.
The authors present an additional case of this rare osseous entity with malignant transformation diagnosed during imaging evaluation of a pathologic fracture of the right upper extremity.
Mazabraud’s syndrome with solitary myxoma and monostotic fibrous dysplasia
A new case of solitary myxoma and monostotic fi brous dysplasia is reported in Mazabraud’s syndrome, where the soft tissue mass and osseous lesions are located in the same anatomical region.
Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome
There may be an increased incidence of malignant transformation in these individuals’ dysplastic bones above that associated with patients suffering from fibrous dysplasia alone.
Mazabraud’s syndrome: Intramuscular myxoma associated with fibrous dysplasia
The association of fibrous dysplasia and intramuscular myxoma is a rare disease known as Mazabraud’s syndrome. Both lesions tend to occur in the same anatomical region. The relationship between
Ollier's disease in association with adjacent fibromatosis
A case of Ollier's disease in association with soft tissue fibromatosis adjacent to the involved upper arm is reported.
Mazabraud’s Syndrome – A Diagnosis Commonly Missed
The report highlights the importance of a high degree of suspicion of this clinical entity in patients treated for recurrent soft tissue swelling as both myxomas and fibrous dysplasia behave differently than their isolated counterparts.
Mazabraud's syndrome. A case with multiple myxomas.
Orbital Fibrous Dysplasia with Soft Tissue Hamartoma—A Variant of Mazabraud's Syndrome
This case may be considered a variant of Mazabraud's Syndrome due to the associated soft tissue lesion with multiple craniofacial bone changes, the associated hamatomatous lesion may be a rare occurrence that should be noted.
Correlative imaging in an atypical case of Mazabraud syndrome.
This work presents an atypical example of the azabraud syndrome and the characteristic difficulties encountered in interpretation of correlative images that necessitated biopsy of the bone and soft-tissue components for a firm diagnosis.


Case report 800: Skeletal fibrous dysplasia associated with intramuscular myxoma (Mazabraud's syndrome).
In summary, intramuscular myxoma associated with fibrous dysplasia of bone represents a benign disorder of uncertain etiology. Magnetic resonance imaging has proved to be a useful diagnostic tool in
Massive intramuscular myxoma associated with fibrous dysplasia of bone.
A massive intramuscular myxoma associated with fibrous dysplasia of the bone in a 70-year-old man was successfully resected. Only 15 such cases of this rare combination of lesions have been reported.
Multiple intramuscular myxomas. Another extraskeletal manifestation of fibrous dysplasia
Ten of the 11 cases had multiple intramuscular myxomas, usually on the right side, and all near but distinct from the bony lesions, all were benign.
Albright's syndrome associated with a soft-tissue myxoma and hypophosphataemic osteomalacia. Report of a case and review of the literature.
A rare case of Albright's syndrome associated with both a soft-tissue myxoma and hypophosphataemic osteomalacia involving fibrous dysplasia and mesenchymal tumours is reported.
Intramuscular Myxoma and fibrous dysplasia of bone — Mazabraud's syndrome
Patients with multiple intramuscular myxomas of the thoracic wall associated with fibrous dysplasia of bone with Mazabraud's syndrome should be preoperatively examined for osseous lesions, according to case history.
The Mazabraud syndrome: case report and review of the literature.
A case of Mazabraud's syndrome is reported in a patient aged 57 years with a history of fibrous dysplasia of the skeletal system which had commenced at the age of 10 and became associated with myxomas of the soft tissues at theage of 42.
[Fibrous dysplasia associated with intramuscular myxoma].
It was not possible to demonstrate a clear correlation between the two lesions, so the authors suggest that myxoma result from bone mechanical disorders.
Osteogenic sarcoma and soft tissue myxoma in a patient with fibrous dysplasia and hemoglobins JBaltimore and S.
It is probable that the rare constellation of findings is in this patient a stochastic event and patients with both fibrous dysplasia and myxomas may be at greater risk for malignant transformation than are individuals with only one of these lesions.
Fibrous dysplasia of the spine, costae and hemipelvis with sarcomatous transformation
A patient with polyostotic fibrous dysplasia and secondary malignant fibrous histiocytoma in a spinal lesion is described.
Intramuscular myxoma--a clinicopathological study of twenty-three cases.
Intramuscular myxoma appears to be a completely benign tumor with characteristics of fibroblastic-myofibroblastics nature of the myxomas, and clinical follow-up revealed no recurrences or metastases.