Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome

@article{LassanceCabral1998PolyostoticFD,
  title={Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome},
  author={Carlos Eduardo Lassance Cabral and Pedro Gabriel Dantas Guedes and Therezinha Fonseca and Jos{\'e} Francisco Neto Rezende and Luiz Celso Cruz Jr. and Julius Smith},
  journal={Skeletal Radiology},
  year={1998},
  volume={27},
  pages={278-282}
}
Abstract Mazabraud’s syndrome, though uncommon, is reported increasingly frequently. It represents an entity readily recognisable radiologically on MR imaging. Awareness of the syndrome, particularly when the myxoma is solitary, can prevent misdiagnosis of intramuscular myxomas (especially when large) as malignant mesenchymal tumors containing myxoid tissue. We review the 34 cases previously reported in the literature and include a recent case from our center. 
Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud’s syndrome
TLDR
An extremely rare combination of a solitary IM and monostotic FD as a variant of Mazabraud’s syndrome is presented, and the importance of recognizing this rare coexistence for appropriate management of the patient is discussed.
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TLDR
The authors present an additional case of this rare osseous entity with malignant transformation diagnosed during imaging evaluation of a pathologic fracture of the right upper extremity.
Mazabraud’s syndrome with solitary myxoma and monostotic fibrous dysplasia
TLDR
A new case of solitary myxoma and monostotic fi brous dysplasia is reported in Mazabraud’s syndrome, where the soft tissue mass and osseous lesions are located in the same anatomical region.
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TLDR
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Mazabraud Syndrome: A Rare Association of Fibrous Dysplasia and Intramuscular Myxomas
TLDR
A 39-year-old female presented to the authors' hospital with complaints of no specific low-grade pain and tenderness of left thigh and leg with small palpable swelling within the left upper thigh with small intramuscular soft tissue swellings which proved to be myxomas on histopathological examination.
Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome
TLDR
There may be an increased incidence of malignant transformation in these individuals’ dysplastic bones above that associated with patients suffering from fibrous dysplasia alone.
Mazabraud’s syndrome: Intramuscular myxoma associated with fibrous dysplasia
The association of fibrous dysplasia and intramuscular myxoma is a rare disease known as Mazabraud’s syndrome. Both lesions tend to occur in the same anatomical region. The relationship between
Ollier's disease in association with adjacent fibromatosis
TLDR
A case of Ollier's disease in association with soft tissue fibromatosis adjacent to the involved upper arm is reported.
Mazabraud’s Syndrome – A Diagnosis Commonly Missed
TLDR
The report highlights the importance of a high degree of suspicion of this clinical entity in patients treated for recurrent soft tissue swelling as both myxomas and fibrous dysplasia behave differently than their isolated counterparts.
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TLDR
Patients with multiple intramuscular myxomas of the thoracic wall associated with fibrous dysplasia of bone with Mazabraud's syndrome should be preoperatively examined for osseous lesions, according to case history.
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TLDR
A case of Mazabraud's syndrome is reported in a patient aged 57 years with a history of fibrous dysplasia of the skeletal system which had commenced at the age of 10 and became associated with myxomas of the soft tissues at theage of 42.
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TLDR
It was not possible to demonstrate a clear correlation between the two lesions, so the authors suggest that myxoma result from bone mechanical disorders.
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TLDR
It is probable that the rare constellation of findings is in this patient a stochastic event and patients with both fibrous dysplasia and myxomas may be at greater risk for malignant transformation than are individuals with only one of these lesions.
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