Polyomino-safe DNA self-assembly via block replacement

  title={Polyomino-safe DNA self-assembly via block replacement},
  author={Chris Luhrs},
  journal={Natural Computing},
The standard abstract model for analyzing DNA self-assembly, aTAM, assumes that single tiles attach one by one to a larger structure. In practice, tiles may attach to each other forming structures called polyominoes and then attach to the assembly using bonds from multiple tiles. Such polyominoes may cause errors in systems designed with only aTAM in mind. In this paper, we first present a formal definition of when one tile system is a “block replacement” of another. Then we present a block… CONTINUE READING