Polynucleotide:Adenosine glycosidase is the sole activity of ribosome-inactivating proteins on DNA.

@article{Barbieri2000PolynucleotideAdenosineGI,
  title={Polynucleotide:Adenosine glycosidase is the sole activity of ribosome-inactivating proteins on DNA.},
  author={Luigi Barbieri and Paola Valbonesi and Flavio Righi and Giampaolo Zuccheri and Federica Monti and Paola Gorini and Bruno Samor{\`i} and Fiorenzo Stirpe},
  journal={Journal of biochemistry},
  year={2000},
  volume={128 5},
  pages={
          883-9
        }
}
Polynucleotide: adenosine glycosidases (PNAG) are a class of plant and bacterial enzymes commonly known as ribosome-inactivating proteins (RIP). They are presently classified as rRNA N-glycosidases in the enzyme nomenclature [EC 3.2.2.22]. Several activities on nucleic acids, other than depurination, have been attributed to PNAG: in particular modifications induced in circular plasmids, including linearisation and topological changes, and cleavage of guanidinic residues. Here we describe a… CONTINUE READING
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