Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.

  title={Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.},
  author={Gerald S. Lazarus and F J Yost and C A Thomas},
  volume={198 4322},
Extracts of involved and uninvolved skin from nine patients with untreated psoriasis were studied for chemotactic activity. Psoriatic plaque contains increased amounts of a complement-dependent chemotactic factor that is inhibited by diisopropyl fluorophosphate. This factor may be human skin serine proteinase. 

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