Polymorphonuclear cells are not sites of persistence of human cytomegalovirus in healthy individuals.

@article{TaylorWiedeman1993PolymorphonuclearCA,
  title={Polymorphonuclear cells are not sites of persistence of human cytomegalovirus in healthy individuals.},
  author={Jean Taylor-Wiedeman and Graham P Hayhurst and J. G. Sissons and John H. Sinclair},
  journal={The Journal of general virology},
  year={1993},
  volume={74 ( Pt 2)},
  pages={265-8}
}
Polymorphonuclear leukocytes (PMNL) have been shown to harbour human cytomegalovirus (HCMV) in viraemic patients, but to date PMNL of asymptomatic healthy subjects have not been examined directly to determine whether this is a normal site of HCMV persistence. Using the polymerase chain reaction (PCR), paired DNA samples prepared from adherent peripheral blood mononuclear cells (PBMC), which are known to be a site of persistence of HCMV, and PMNL of 10 healthy adults were analysed. All of seven… CONTINUE READING

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A test of human cDNA synthesis by the polymerase chain reaction

  • L M.
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