Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility

@article{Tander2008PolymorphismsOT,
  title={Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility},
  author={Berna Tander and Sezgin Gunes and Omer Boke and Gamze Alayli and Nurten Kara and Hasan Bagci and Ferhan Canturk},
  journal={Rheumatology International},
  year={2008},
  volume={28},
  pages={685-691}
}

• Berna Tander, Sezgin Gunes, +4 authors Ferhan Canturk
• Published 2008 in Rheumatology International
• DOI:10.1007/s00296-008-0525-8

Genetic and environmental factors are thought to play roles in the etiopathology of fibromyalgia syndrome (FMS). The objective of this study was to determine the potential effects of single nucleotide polymorphisms (SNPs) in catechol-O-methyltransferase (COMT) (rs4680) and 5-hydroxytryptamine (serotonin) 2A (5-HT2A) receptor (rs6313 and rs6311) genes on susceptibility to FMS. One hundred seventy-one women (80 FMS, 91 control) were enrolled in the study. Polymerase chain reaction-restriction… CONTINUE READING

Save to Library

Create Alert

Cite

View on Springer