Polymorphisms of the Macrophage Inhibitory Factor and C-Reactive Protein Genes in Subjects with Alzheimer’s Dementia

@article{Flex2004PolymorphismsOT,
  title={Polymorphisms of the Macrophage Inhibitory Factor and C-Reactive Protein Genes in Subjects with Alzheimer’s Dementia},
  author={Andrea Flex and Roberto Pola and Michele Serricchio and Eleonora Gaetani and Anna S. Proia and Angela Di Giorgio and Pierangelo Papaleo and Roberto Bernabei and P Boggio Pola},
  journal={Dementia and Geriatric Cognitive Disorders},
  year={2004},
  volume={18},
  pages={261 - 264}
}
  • Andrea Flex, Roberto Pola, +6 authors P Boggio Pola
  • Published in
    Dementia and Geriatric…
    2004
  • Medicine
  • Neuroinflammation is a central feature of Alzheimer’s disease (AD). C-reactive protein (CRP) is a key molecule of the acute phase of inflammation that has been localized in the two characteristic lesions of AD brain, senile plaque and neurofibrillary tangles. On the other hand, the macrophage migration inhibitory factor (MIF) is a cytokine with multiple biological activities, including the ability to act as potent amyloid beta (A-beta)-binding protein. Two common polymorphisms have been… CONTINUE READING

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    Evaluation of inflammation-related genes polymorphisms in Mexican with Alzheimer’s disease: a pilot study

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