Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women

@article{Shi2012PolymorphismsOT,
  title={Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women},
  author={Ting-Yan Shi and Mei-ling Zhu and Jing He and Meng-Yun Wang and Qiaoxin Li and Xiao-yan Zhou and Menghong Sun and Z. Shao and K. Yu and Xi Cheng and Xiaohua Wu and Q. Wei},
  journal={Human Genetics},
  year={2012},
  volume={132},
  pages={301-312}
}
Interleukin 6 (IL6) encodes a cytokine protein, which functions in inflammation, maintains immune homeostasis and plays important roles in cervical carcinogenesis. Single nucleotide polymorphisms (SNPs) in IL6 that cause variations in host immune response may contribute to cervical cancer risk. In this two-stage case–control study with a total of 1,584 cervical cancer cases and 1,768 cancer-free female controls, we investigated associations between two IL6 SNPs and cervical cancer risk in… Expand
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