Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study.

@article{Almeida2009PolymorphismsOT,
  title={Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study.},
  author={Osvaldo P. Almeida and Paul E. Norman and Richard Allcock and Frank M. van Bockxmeer and Graeme J. Hankey and Konrad Jamrozik and Leon Flicker},
  journal={International journal of epidemiology},
  year={2009},
  volume={38 4},
  pages={1049-59}
}
BACKGROUND Depression has been associated with chronic changes in the serum concentration of C-reactive protein (CRP) in observational studies, but it is unclear if this association is causal or is due to confounding and bias. Genetic studies are less subject to this type of error and offer an opportunity to investigate if CRP is causally linked to depression, particularly because known polymorphisms of the CRP gene have been associated with high- and low-basal serum concentrations of CRP… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

PLoS ONE 2008;3:e3011

  • C Marsik, L Kazemi-Shirazi, T Schickbauer
  • 2008

Similar Papers

Loading similar papers…