Polymorphisms of interleukin (IL)-1alpha, IL-1beta, IL-6, IL-10, and IL-18 and the risk of ovarian cancer.

@article{Bushley2004PolymorphismsOI,
  title={Polymorphisms of interleukin (IL)-1alpha, IL-1beta, IL-6, IL-10, and IL-18 and the risk of ovarian cancer.},
  author={Abigail W. Bushley and Robert F. Ferrell and Katharine E. McDuffie and Keith Y Terada and Michael E. Carney and Pamela J. Thompson and Lynne Ross Wilkens and Ko-Hui Tung and Roberta B. Ness and Marc T. Goodman},
  journal={Gynecologic oncology},
  year={2004},
  volume={95 3},
  pages={672-9}
}
OBJECTIVE Recent studies of ovarian cancer have suggested a role for inflammation in carcinogenesis. Data from a population-based case-control study in Hawaii were examined to assess the relation between polymorphisms in cytokines involved with the inflammatory response, specifically members of the interleukin (IL) family and the incidence of ovarian cancer. PATIENTS AND METHODS The analysis of 182 epithelial ovarian cancer cases and 219 controls focused on the polymorphisms in the following… CONTINUE READING