Polymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndrome

@article{Xu2009PolymorphismsOT,
  title={Polymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndrome},
  author={Pei Yu Xu and Yena Che and Yun-xia Cao and Xiaoke Wu and Haixiang Sun and Feng-jing Liang and Jing Sun and L H Ke and Long Yi and Yong Wang},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2009},
  volume={27},
  pages={23-28}
}
This study was to evaluate whether polymorphisms of TCF7L2 (rs7903146) and HHEX (rs1111875) genes responsible for insulin secretion are associated with the polycystic ovary syndrome (PCOS) in Chinese people. 326 PCOS patients and 290 healthy individuals as controls were studied. Blood samples were obtained for DNA analyses and hormone measurements. Genotyping of the TCF7L2 (rs7903146) and HHEX (rs1111875) genes was carried out by the polymerase chain reaction–restriction fragment length… CONTINUE READING
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