Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in Northeastern Thais

@article{Romphruk2009PolymorphismsON,
  title={Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in Northeastern Thais},
  author={A V Romphruk and Amornarat Romphruk and Taeko K. Naruse and Sarayot Raroengjai and Chintana Puapairoj and Hidetoshi Inoko and Chanvit Leelayuwat},
  journal={Immunogenetics},
  year={2009},
  volume={61},
  pages={611-617}
}
Unique long 16 (UL-16)-binding proteins (ULBP) or retinoic acid early transcripts-1 (RAET1) are ligands to the activating receptor, NKG2D. The human RAET1/ULBP gene family is identified as ten members (RAET1E to N) with six loci encoding for potentially functional proteins. These are ULBP1 or RAET1I, ULBP2 or RAET1H, ULBP3 or RAET1N, and RAET1L, which are glycosylinositol phospholipid (GPI)-linked glycoproteins and ULBP4 or RAET1E and ULBP5 or RAET1G, which are transmembrane glycoproteins. The… CONTINUE READING
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