Polymorphisms of IKBKE gene are associated with major depressive disorder and panic disorder

Abstract

BACKGROUND The immune system has been increasingly implicated in the development of mood and anxiety disorders. Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase epsilon (IKBKE) gene encodes IKKε protein that is involved in innate immunity, predominantly antiviral response generation. It also bears pro-inflammatory properties that could… (More)
DOI: 10.1002/brb3.314

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