Polymorphisms of ECE1 May Contribute to Susceptibility to Ischemic Stroke in Han Chinese of Northern China

@article{Sui2013PolymorphismsOE,
  title={Polymorphisms of ECE1 May Contribute to Susceptibility to Ischemic Stroke in Han Chinese of Northern China},
  author={Rubo Sui and Zhiyi He},
  journal={Cell Biochemistry and Biophysics},
  year={2013},
  volume={69},
  pages={237-246}
}
Endothelin (ET) converting enzyme 1 (ECE1) is well known for its critical role in the process of ET. Recent studies have demonstrated that two genetic variants of ECE1 gene, rs212528 and rs213045 (C338A), are associated with hypertension and atherosclerosis formation. To investigate the association between the ECE1 gene polymorphisms and ischemic stroke (IS) in Chinese population. With a candidate loci strategy, we conducted a case–control study involving 381 IS cases and 366 non-IS controls in… CONTINUE READING
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Stroke genetics. Human Molecular Genetics, 20(R2), R124–R131

  • H. S. Markus
  • 2011
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