Polymorphisms of DQ β genes in HLA-DR4 haplotypes from healthy and diabetic individuals

Abstract

The restriction fragment length polymorphism (RFLP) of DQ β was assessed in a panel of control and insulin-dependent diabetes (IDD) patients who were serologically typed as HLA-DR4 homozygotes or HLA-DR3, DR4 heterozygotes. Digestions of genomic DNA with Barn HI, Bg1 II, Pst I, Xba I, and Hind III revealed a total of 15 RFLPs in the panel of 71 HLA-DR4… (More)
DOI: 10.1007/BF00344028

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@article{Henson1987PolymorphismsOD, title={Polymorphisms of DQ β genes in HLA-DR4 haplotypes from healthy and diabetic individuals}, author={Vickie Henson and Noel K. Maclaren and William Riley and Edward K. Wakeland}, journal={Immunogenetics}, year={1987}, volume={25}, pages={152-160} }