Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer

@inproceedings{Cha2007PolymorphismsOC,
  title={Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer},
  author={In-Ho Cha and Jong Y. Park and Won-Yoon Chung and Min-Ah Choi and Hyung Jun Kim and K Park},
  booktitle={Yonsei medical journal},
  year={2007}
}
PURPOSE Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral cancer is tobacco use, we hypothesized that polymorphic genes coding for tobacco carcinogen-metabolizing enzymes may play a role in oral cancer susceptibility. MATERIALS AND METHODS To investigate the association between polymorphisms of the CYP1A1 and GSTM1 genes and risks for oral squamous cell carcinoma (OSCC) in the Korean… CONTINUE READING

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