Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne.

@article{Paraskevaidis1998PolymorphismsIT,
  title={Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne.},
  author={A Paraskevaidis and Nikolaos Drakoulis and Ivar Roots and Constantin E. Orfanos and C C Zouboulis},
  journal={Dermatology},
  year={1998},
  volume={196 1},
  pages={171-5}
}
Cytochromes P-450 are a supergene family of enzymes involved in the metabolism of a wide range of endogenous and foreign compounds. The existing genetic variations of the distinct isozymes lead to interindividually different metabolic capacity. Since vitamin A, endogenous retinoids and their natural metabolites are morphogenic for the sebaceous gland, we investigated the polymorphisms of cytochrome P-450 1A1, as being one of the most active isozymes involved in their interconversion. From the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…