Polymorphisms in the SAA1/2 Gene Are Associated with Carotid Intima Media Thickness in Healthy Han Chinese Subjects: The Cardiovascular Risk Survey

@article{Xie2010PolymorphismsIT,
  title={Polymorphisms in the SAA1/2 Gene Are Associated with Carotid Intima Media Thickness in Healthy Han Chinese Subjects: The Cardiovascular Risk Survey},
  author={Xiang Xie and Yi-Tong Ma and Yining Yang and Zhen-Yan Fu and Xiao-Mei Li and Ding Huang and Xiang Ma and Bang-dang Chen and Fen Liu},
  journal={PLoS ONE},
  year={2010},
  volume={5}
}
Background Serum amyloid A protein (SAA) is not only an inflammatory factor, but also an apolipoprotein that can replace apolipoprotein A1 (apoA1) as the major apolipoprotein of high-density lipoprotein (HDL), which has been linked to atherosclerosis. However, the relationship between genetic polymorphisms of SAA and the intima-media thickness (IMT) of the common carotid artery in healthy subjects remains unclear. We investigated the role of SAA1 and SAA2 gene polymorphisms with IMT in a cohort… Expand
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