Polymorphisms in the NMDA subunit 2B are not associated with alcohol dependence and alcohol withdrawal–induced seizures and delirium tremens


Ethanol–inhibited glutamatergic neurotransmission has been shown to mediate pathophysiological mechanisms in the development of alcoholism, including withdrawal symptoms. NMDA–receptor 2B (NR2B) is a subunit that confers a high sensitivity to ethanol–induced inhibition. Previously we had reported a lack of association between the single nucleotide… (More)
DOI: 10.1007/s00406-004-0545-7


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