Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma.

@article{Dybdahl1999PolymorphismsIT,
  title={Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma.},
  author={Marianne Dybdahl and Urlich Vogel and Gerda Frentz and H{\aa}kan Wallin and Bj{\o}rn A Nex{\o}},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={1999},
  volume={8 1},
  pages={
          77-81
        }
}
The XPD protein has a dual function, both in nucleotide excision repair and in basal transcription. We have studied the role of two nucleotide substitutions in the XPD gene, one in exon 23 leading to an amino acid substitution (Lys751Gln) and one silent in exon 6 in relation to basal cell carcinoma (BCC). Both are two-allele polymorphisms, with the nucleobases A and C at the given positions. We genotyped psoriasis patients with and without BCC and nonpsoriatic persons with and without BCC (4 x… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 69 CITATIONS, ESTIMATED 45% COVERAGE

The Polymorphism of DNA Repair Gene ERCC2/XPD Arg156Arg and Susceptibility to Breast Cancer in a Chinese Population

  • Biochemical Genetics
  • 2009
VIEW 8 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED

Polymorphisms of the XRCC1 and XPD Genes and Breast Cancer Risk: A Case-Control Study

  • Pathology & Oncology Research
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of Basal cell carcinoma.

  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 2002
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Nucleotide excision repair and cancer

  • Journal of Molecular Histology
  • 2006
VIEW 2 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2001
2018

CITATION STATISTICS

  • 9 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 17 REFERENCES

Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality

J. de Boer, I. Donker, J. de Wit, J. H. Hoeijmakers, G. Weeda
  • Cancer Res.,
  • 1998
VIEW 1 EXCERPT

Seasonal variation of DNA damage and repair in patients with nonmelanoma skin cancer and referents with and without psoriasis

P. Moller, L. E. Knudsen, +3 authors B. A. Nexo
  • Mutat . Res .
  • 1998
VIEW 1 EXCERPT

Evolution of codon usage bias in Drosophila.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1997

Similar Papers

Loading similar papers…