Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified.

@article{Addington2004PolymorphismsIT,
  title={Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified.},
  author={Anjen{\'e} M Addington and Michele C Gornick and Alexandra L Sporn and Nitin Gogtay and Deanna K. Greenstein and Marge C Lenane and Peter A. Gochman and Natalie Baker and Rishi Balkissoon and Radha Krishna Vakkalanka and Daniel R. Weinberger and Richard E Straub and Judith L. Rapoport},
  journal={Biological psychiatry},
  year={2004},
  volume={55 10},
  pages={976-80}
}
BACKGROUND Childhood-onset schizophrenia (COS), defined as onset of psychotic symptoms by age 12 years, is a rare and severe form of the disorder that seems to be clinically and neurobiologically continuous with the adult disorder. METHODS We studied a rare cohort consisting of 98 probands; 71 of these probands received a DSM-defined diagnosis of schizophrenia, and the remaining 27 were diagnosed as psychosis not otherwise specified (NOS) (upon 2-6 year follow-up, 13 have subsequently… CONTINUE READING

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