Polymorphisms in telomere maintenance genes and risk of lung cancer.

@article{Choi2009PolymorphismsIT,
  title={Polymorphisms in telomere maintenance genes and risk of lung cancer.},
  author={Jin Eun Choi and H S Kang and Jin Sung Jang and Yi Young Choi and Min Jung Kim and Jong Sik Kim and Hyo-Sung Jeon and Won Kee Lee and Seung Ick Cha and Chang Ho Kim and Sin Kam and Tae Hoon Jung and Jae Yong Park},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2009},
  volume={18 10},
  pages={2773-81}
}
This study was conducted to comprehensively evaluate the associations between polymorphisms in telomere maintenance genes (TERT, TRF1, TNKS1, TRF2, RAP1, and POT1) and lung cancer risk. We captured 35 polymorphisms in the genes and determined their frequencies in 27 healthy Koreans. Ten haplotype-tagging polymorphisms were examined in a case-control study that consisted of 720 lung cancer patients and 720 healthy controls. The TERT rs2735940 g.C > T and rs2736098 g.G > A, and TNKS1 rs6985140 g… CONTINUE READING

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PL,Afshari C, Barrett JC.Cloning and characterization v 2009;18(10)

  • I Horikawa, Cable
  • Cancer Res
  • 2009
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