Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects.

Abstract

OBJECTIVE To investigate the associations between biomarkers and genetic variants involved in homocysteine metabolism and the risk of complex birth defects. METHODS Total homocysteine (tHcy), folate, cobalamin, apo-transcobalamin (apo-TC) and apo-haptocorrin (apo-HC) were measured in the amniotic fluid of 82 women who were pregnant with a child having a… (More)
DOI: 10.1002/pd.2006

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Cite this paper

@article{Brouns2008PolymorphismsIG, title={Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects.}, author={Raf Brouns and Nicolette T. C. Ursem and Jan Willem Lindemans and W. Hop and S M F Pluijm and E A P Steegers and R{\'e}gine P M Steegers-Theunissen}, journal={Prenatal diagnosis}, year={2008}, volume={28 6}, pages={485-93} }