Polymorphisms in genes in the RANKL/RANK/OPG pathway are associated with bone mineral density at different skeletal sites in post-menopausal women

@article{Tu2014PolymorphismsIG,
  title={Polymorphisms in genes in the RANKL/RANK/OPG pathway are associated with bone mineral density at different skeletal sites in post-menopausal women},
  author={P-h Tu and P. Duan and R.-S. Zhang and D. Xu and Yanbo Wang and H.-P. Wu and Y.-H. Liu and L. -Z. Si},
  journal={Osteoporosis International},
  year={2014},
  volume={26},
  pages={179-185}
}
Association between 22 single nucleotide polymorphisms (SNPs) in the TNFSF11, TNFRSF11A, and TNFRSF11B genes in the RANKL/RANK/OPG pathway with bone mineral density (BMD) in 881 post-menopausal women. Our results suggest that TNFSF11 and TNFRSF11A, but not TNFRSF11B, genetic polymorphisms influence BMD mainly in the femoral neck in post-menopausal Chinese women. The aim of this study was to assess the relationship of polymorphisms in the TNFSF11, TNFRSF11A, and TNFRSF11B genes in the RANKL/RANK… CONTINUE READING
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