Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.

@article{Arai2005PolymorphismsIF,
  title={Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.},
  author={Hidenori Arai and Akira Yamamoto and Yuji Matsuzawa and Yasushi Saito and Nobuhiro Yamada and Shinichi Oikawa and Hiroshi Mabuchi and Tamio Teramoto and Jun Sasaki and N. Nakaya and Hiroshige Itakura and Yuichi Ishikawa and Yasuyoshi Ouchi and Hiroshi Horibe and Tohru Egashira and Hiroaki Hattori and Nobuo Shirahashi and Toru Kita},
  journal={Journal of atherosclerosis and thrombosis},
  year={2005},
  volume={12 5},
  pages={240-50}
}
We studied the association of six common polymorphisms of four genes related to lipid metabolism with serum lipid levels. We selected single-nucleotide polymorphisms (SNPs) in the genes for cholesteryl ester transfer protein (CETP), lipoprotein lipase (LPL), hepatic lipase (LIPC), and apolipoprotein CIII (APOC3), and studied 2267 individuals randomly selected from the participants of Serum Lipid Survey 2000. There was a significant association of CETP polymorphism (D442G, Int14 +1 G --> A, and… CONTINUE READING

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