Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults.

@article{Rajaraman2007PolymorphismsIA,
  title={Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults.},
  author={Preetha Rajaraman and Sophia Wang and Nathaniel Rothman and Mallory McClester Brown and Peter Mcl. Black and Howard A. Fine and Jay S. Loeffler and Robert G. Selker and William R. Shapiro and Stephen J Chanock and Peter D. Inskip},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2007},
  volume={16 8},
  pages={
          1655-61
        }
}
Despite the potential importance of the cell cycle and apoptosis pathways in brain tumor etiology, little has been published regarding brain tumor risk associated with common gene variants in these pathways. Using data from a hospital-based case-control study conducted by the National Cancer Institute between 1994 and 1998, we evaluated risk of glioma (n = 388), meningioma (n = 162), and acoustic neuroma (n = 73) with respect to 12 single nucleotide polymorphisms from 10 genes involved in… CONTINUE READING

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