Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.

@article{Crimmins2007PolymorphismsIA,
  title={Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.},
  author={Nancy A. Crimmins and Luc J Martin},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  year={2007},
  volume={8 5},
  pages={419-23}
}
Adiponectin plays an important role in insulin sensitivity via adiponectin receptor 1 and 2 signalling. To date, six genetic association studies have examined the role of polymorphisms in the adiponectin receptor 1 and 2 genes (ADIPOR1 and ADIPOR2) in insulin resistance and type 2 diabetes. These studies are summarized in this review along with unpublished data from the authors. In addition, these polymorphism studies are used to illustrate some of the potential pitfalls and reasons for poor… CONTINUE READING
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