Polymorphisms in XRCC1 gene, alcohol drinking, and risk of colorectal cancer: a case-control study in Jiangsu Province of China.

@article{Gao2014PolymorphismsIX,
  title={Polymorphisms in XRCC1 gene, alcohol drinking, and risk of colorectal cancer: a case-control study in Jiangsu Province of China.},
  author={Chang-ming Gao and Jianhua Ding and Su-ping Li and Yan-ting Liu and Hai-xia Cao and Jian-Zhong Wu and Jin-Hai Tang and Kazuo Tajima},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2014},
  volume={14 11},
  pages={6613-8}
}
To evaluate the relationship between alcohol drinking, XRCC1 codon 194 and 399 polymorphisms and risk of colorectal cancer, we conducted a case-control study with 315 colorectal cancer cases (105 colon, 210 rectal) and 439 population-based controls in Jiangsu Province of China. The XRCC1 codon 194 and 399 genotypes were identified using polymerase chain reaction and restrictrion fragment length polymorphism methods (PCR-RFLP). A structured questionnaire was used to elicit detailed information… CONTINUE READING
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